HALL OF FAME / inventor profile

Robert Samuel Langer, Jr.
Born August 29, 1948

Systems for the Controlled Release of Macromolecules; High Molecular Weight Polyanhydride and Preparation Thereof
Patent Numbers 4,391,797 and 4,757,128

Inducted 2006

Robert Langer revolutionized biomedical technology through the development of a controlled drug delivery system.

Invention Impact

Langer made numerous improvements on his controlled delivery system. Designing a chemotherapy wafer for the treatment of brain cancer, he was able to administer slow releasing cancer-killing medication directly where the cancerous tumor had been removed. He also pioneered a variety of remotely controlled drug delivery systems that vary the amount of drug released through electric impulse, ultrasound, and magnetic field.

Holder of over 300 U.S. and foreign patents, Langer's controlled drug delivery innovations are the basis of a multibillion dollar industry in the United States. An Institute Professor at the Massachusetts Institute of Technology, Langer was recognized in 1998 with the Lemelson-MIT Prize, being cited as one of history's most prolific inventors in medicine.

Inventor Bio

Langer was born in Albany, New York. After earning his doctorate at MIT in 1974, he began developing a system for delivering inhibitors to cancerous tumors. Langer discovered a way to control the delivery of large molecule drugs by using both nondegradable and biodegradable polymers to engineer synthetic materials that allow for precisely timed chemical release.

© 2006 National Inventors Hall of Fame