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Michel Mirowski
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Morton Mower
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M. Stephen Heilman
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Alois Langer
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Today, Vice President Dick Cheney is one of the hundreds of thousands of people worldwide whose life has been saved because of the collaborative power of a few inventive minds.

The implantable defibrillator, an electronic device to monitor and correct abnormal heart rhythms, has come a long way since its first successful implant in 1980. Today, more than 300,000 patients have received an implantable defibrillator, which is proven to be 99 percent effective in treating sudden cardiac arrest.

Mirowski’s idea for the device was prompted by the death of his friend, colleague and mentor, Dr. Harry Heller. Heller was the head of medicine at the hospital in Israel where Mirowski completed his internship and residency. Heller helped him obtain two fellowships, one of which was at Johns Hopkins in Baltimore. While in Baltimore, Mirowski learned that his friend suffered an attack of ventricular fibrillation. He knew Heller was still alive but knew an attack would happen again. Refusing to stay in the hospital, and not able to be followed around by a defibrillator, Heller died several weeks later during dinner with his family.

This loss motivated Mirowski to develop an AICD and find a way to help those people who needed continuous heart monitoring and treatment. In 1968, now head of Sinai Hospital’s Coronary Care Unit, Mirowski met Mower, a Research Associate in the Cardiopulmary Laboratory, and they began to work on turning the idea into a reality. In 1973, Mirowski partnered with Heilman, founder of Medrad, a company devoted to developing clinically useful medical devices, to help make Mirowski’s vision a reality. Heilman also identified Langer because of his work on electrocardiograph signal analysis, completing the team of four pioneers.

Normally, a natural pacemaker within the heart regularly stimulates the heart to contract, producing a heartbeat. Ventricular fibrillation occurs when different impulses from the heart’s ventricles signal the heart to beat abnormally, causing very little blood to be pumped through the heart to the brain and body, which can result in sudden cardiac death.

To correct this condition, this team of doctors designed and tested the first automatic, implantable defibrillator and the first alternative to drugs and surgery. The device, which corrects the irregular rhythm, was originally the size of deck of cards and weighing nine ounces. Although these devices have gotten smaller and smaller since first patented, the technology from the original patent has not been replaced by new or improved technology.


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